Desloratadine is an Antihistamine Used to Relieve Allergy

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Desloratadine is an Antihistamine Used to Relieve Allergy

Clarinex contain Desloratadine is a medicine used to treat allergies. It is marketed under several trade names such as NeoClarityn, Claramax, Larinex, Aerius, Dazit, Azomyr, Deselex and Delot. It is an active metabolite of loratadine, which is also on the market.

Mechanism of action:It is a tricyclic antihistamine, which has a selective and peripheral H1-antagonist action. It is an antagonist at histamine H1 receptors, and an antagonist at all subtypes of the muscarinic acetylcholine receptor. It has a long-lasting effect and in moderate and low doses, does not cause drowsiness because it does not readily enter the central nervous system. Unlike other antihistamines, desloratadine is also effective in relieving nasal congestion, particularly in patients with allergic rhinitis.

Contraindications:Do not take this medication if you:

  • are allergic to atenolol or any ingredients of the drug
  • have a situation known as pheochromocytoma (in the absence of alpha-blockade)
  • have a condition known as right ventricular failure caused by pulmonary hypertension
  • have a condition known as “sick sinus syndrome”
  • have a very slow heart rate
  • have congestive heart failure
  • have metabolic acidosis
  • have serious heart block
  • have severe peripheral arterial disorders (blockage of blood flow to limbs of body)
  • have very low blood pressure

Side effects:

  • back pain or joint pain
  • breathing difficulty or breathless
  • cold hands and feet
  • understanding disorder (especially in seniors)
  • depression
  • dizziness or lightheadedness when getting up from a lying or sitting position
  • fever and sore throat
  • hallucinations
  • swelling of ankles, feet, or lower legs
  • symptoms of liver damage (such as yellow skin or eyes, abdominal pain, dark urine, clay-coloured stools, loss of appetite, nausea and vomiting, or itching).


  • These tablets are available in three different strengths – 25 mg, 50 mg and 100 mg. Each time you collect a fresh supply of tablets, it's a good idea to check the strength on the packet to make sure they are the strength you are expecting.
  • Try to take it at the same time of day each day, as this will help you to remember to take it.
  • If you forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.

Storage:Store at room temperature. Protect from heat, light and moisture. Keep away from reach of children.

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